DSM to TYS (Des Moines to Knoxville) Flights

Last Minute Flights from DSM to TYS

Price found within the past 7 days for the specified period. Click for updated prices.

OriginDestinationTravel DatesFlights From*
DSMAlcoaMay 3 to May 9$354
*Prices include taxes and fees

Cheapest DSM to TYS Flights

Price found within the past 7 days for the specified period. Click for updated prices.

OriginDestinationTravel DatesFlights From*
DSMAlcoaMay 28 to May 30$217
DSMAlcoaMay 24 to May 26$224
DSMAlcoaMay 28 to June 6$233
DSMAlcoaOctober 14 to October 18$249
*Prices include taxes and fees
DSM to TYS Flight Details
Origin airport
Des Moines Intl.
Origin airport IATA code
DSM
Destination airport
McGhee Tyson
Destination airport IATA code
TYS
Distance
653 mi

Frequently asked questions

What airlines fly direct from Des Moines Intl. Airport (DSM) to TYS?
Unfortunately, there aren’t any airlines that fly straight from Des Moines Intl. Airport to Knoxville Airport. You’ll have to reserve a journey with one or more stops.
How many flights are there from DSM to TYS?
Approximately 27 services are available each day from Des Moines, IA (DSM-Des Moines Intl.) to Knoxville, TN (TYS-McGhee Tyson). Fasten your safety belt because your plane to Alcoa is ready to take off.
How long does it take to fly from Des Moines, IA (DSM-Des Moines Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
While you won’t be squished in your seat for a lifetime from Des Moines, IA (DSM-Des Moines Intl.) to Knoxville, TN (TYS-McGhee Tyson), 4 hours and 13 minutes is no quick trip either. Think about upgrading your airfare if you’d like the comfort of a few extra inches of room.
What is the flight distance from Des Moines, IA (DSM-Des Moines Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
It’s only 650 miles (1,050 1) from Des Moines, IA (DSM-Des Moines Intl.) to Knoxville, TN (TYS-McGhee Tyson), making it a short-haul journey. Try to secure a window seat and be wowed by the bright lights of Alcoa as you fly in.
How many morning flights are there from DSM to TYS?
Early risers — you’ll be happy to discover that there are 99 morning flights from DSM to TYS each week.

  • If you’re eager to travel with American Airlines (AA), it has 43 weekly flights that set off before noon. The 5:00AM flight is the first of the day.
  • United Airlines (UA) is another excellent option to consider. It has 35 morning services, with the earliest departing at 6:00AM.
  • Leave before noon with Delta Air Lines (DL) and you’ll have 21 flights a week to pick from. 5:33AM is the earliest you can take off from DSM to TYS.

How many afternoon flights are there from DSM to TYS?
Jet away on one of the 92 afternoon and evening flights from DSM to TYS each week.

  • Grab a ticket with American Airlines (AA), which has 33 flights each week that leave after midday. 12:02PM is the earliest of those flights.
  • If you’d prefer to make a booking with United Airlines (UA), you can take your pick of 31 weekly afternoon and evening flights that depart from 1:40PM onward.
  • Alternatively, pack your suitcase and go with Delta Air Lines (DL). This airline has 27 flights per week after midday, with the earliest departing at 12:00PM.

What is the earliest departure time out of Des Moines to Alcoa?
The earliest flight flies from DSM at 5:00AM and arrives at TYS at 10:59PM. Be sure to give yourself sufficient time in the morning to easily get to the airport.
What is the latest departure time out of Des Moines to Alcoa?
Secure a ticket for the 6:37PM flight from DSM, touching down at 3:50PM at TYS, and give yourself time to take care of any last-minute vacation preparations. This is the latest flight you can get on this route.
What is the average price from Des Moines to Alcoa?
Round-trip fares between DSM and TYS start from around $217. When you’re ready to take off, we’ll help you walk away with the best deal in town. This price was available on Flights.com within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Des Moines to Knoxville Flights

Whether it’s for an obligation or the sake of your sanity, sometimes you need to get away. Maybe you need flights from Des Moines to Knoxville to attend your cousin’s wedding, to pitch a business idea to your boss, or simply treat yourself to a mini vacation. Regardless of the reasons behind packing your bags and needing to find our cheapest flights from DSM to TYS, we’ve got you covered here at Flights.com.

We present you with some of the most affordable deals on airfare, so stop that Google flights search. We want you to spend less on your flight from Des Moines to Knoxville, so you can spend more during your getaway. With Flights.com, you’ll find it simple to land airline tickets with itineraries matching your travel schedule. What’s more, we provide you with all the information you need to confidently make reservations on your family, business, or personal trip.