DSM to STL (Des Moines to St. Louis) Flights

Last Minute Flights from DSM to STL

Price found within the past 7 days for the specified period. Click for updated prices.

OriginDestinationTravel DatesFlights From*
DSMSt. LouisMarch 14 to March 16$390
*Prices include taxes and fees

Cheapest DSM to STL Flights

Price found within the past 7 days for the specified period. Click for updated prices.

OriginDestinationTravel DatesFlights From*
DSMSt. LouisMarch 17 to March 24$234
DSMSt. LouisApril 9 to April 12$237
DSMSt. LouisApril 14 to April 15$243
DSMSt. LouisApril 14 to April 15$243
DSMSt. LouisApril 7 to April 8$273
*Prices include taxes and fees
DSM to STL Flight Details
Origin airport
Des Moines Intl.
Origin airport IATA code
DSM
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Distance
259 mi

Frequently asked questions

What airlines fly direct from Des Moines Intl. Airport (DSM) to Lambert-St. Louis Intl. Airport (STL)?
No air carriers fly straight from Des Moines Intl. Airport to Lambert-St. Louis Intl. Airport (STL). To reach St. Louis, you'll need to get a flight with one or more stops.
How many flights are there from DSM to STL?
There are no less than 33 flights every day from Des Moines, IA (DSM-Des Moines Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.), so you have no shortage of ways to get to St. Louis. Just pick out a date that works best for you and lock in your seat.
How long does it take to fly from Des Moines, IA (DSM-Des Moines Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
From Des Moines, IA (DSM-Des Moines Intl.), it's an easy 4 hours and 22 minutes to St. Louis, MO (STL-Lambert-St. Louis Intl.). Don't get too comfortable in your seat — you'll be landing at your destination before you know it.
What is the flight distance from Des Moines, IA (DSM-Des Moines Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The short-haul journey from Des Moines to St. Louis is just 260 miles (420 1). Don't get too comfortable though — you'll be touching down at St. Louis, MO (STL-Lambert-St. Louis Intl.) not long after taking off!
How many morning flights are there from DSM to STL?
Early risers, you'll be happy to discover that there are 120 morning flights from DSM to STL each week.

  • American Airlines (AA) operates around 50 weekly flights that take off before noon. The earliest is 5:00AM.
  • Delta Air Lines (DL) is another popular option. It has 35 morning flights, with the earliest jetting out at 5:33AM.
  • You'll have approximately 35 morning flights to take your pick of if you book a ticket with United Airlines (UA). 6:00AM is the earliest departure time.

How many afternoon flights are there from DSM to STL?
With 117 afternoon and evening flights from DSM to STL a week, you can forget about setting your alarm early.

  • American Airlines (AA) has 43 weekly flights that leave after midday. The earliest departs at 12:02PM.
  • If you want to journey with Delta Air Lines (DL), there are 39 weekly afternoon and evening flights that depart DSM from 12:00PM onward.
  • Otherwise you can jet out from 1:40PM onward with United Airlines (UA). This airline has 31 afternoon and evening flights each week.

What is the earliest departure time out of Des Moines to St. Louis?
The earliest flight sets off from DSM at 5:00AM and hits the runway at 11:00PM at STL. Don't forget to give yourself sufficient time in the morning to easily get to your departure gate.
What is the latest departure time out of Des Moines to St. Louis?
From DSM, the latest flight you can catch takes off at 6:37PM and lands at STL at 3:46PM. If you don't do early starts, this is the flight to book.
What is the average price from Des Moines to St. Louis?
The average lowest price for a round-trip airfare from DSM to STL is $234. Walk away with your own deal by booking your tickets today. This price was available on Flights.com within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Des Moines to St. Louis Flights

Whether it’s for an obligation or the sake of your sanity, sometimes you need to get away. Maybe you need flights from Des Moines to St. Louis to attend your cousin’s wedding, to pitch a business idea to your boss, or simply treat yourself to a mini vacation. Regardless of the reasons behind packing your bags and needing to find our cheapest flights from DSM to STL, we’ve got you covered here at Flights.com.

We present you with some of the most affordable deals on airfare, so stop that Google flights search. We want you to spend less on your flight from Des Moines to St. Louis, so you can spend more during your getaway. With Flights.com, you’ll find it simple to land airline tickets with itineraries matching your travel schedule. What’s more, we provide you with all the information you need to confidently make reservations on your family, business, or personal trip.

Plan Your Trip